TAG FLEX-LB™ “TFLB”
A RUO Stabilizing Blood Collection Tube (BCT)
A New Standard in Pre-Analytical Stability
for Liquid Biopsy
Protect Your Science. Perfect Your Signal.
TAG FLEX-LB™ is a research-use 10 mL blood collection tube that keeps cell-free DNA and RNA stable for 7 days at room temperature, and its plasma needs no Proteinase K digestion before cfDNA extraction.
Sample Degradation Begins at Collection. Your Results Are at Risk.
Pre-analytical variability is a primary source of failure in liquid biopsy. Sample degradation obscures critical biomarker signals with contaminants from dying cells, leading to irreproducible results and costly assay failures. Like other preservative tubes, TFLB does not need the 2- to 4-hour processing window that K2EDTA requires (Leest 2024), so samples drawn late in the day or before a weekend can wait for the next scheduled run.
What TFLB Changes, From Collection to Analysis.
Room-Temperature Stability
cfDNA and cfRNA stable for 7 days at 20 to 22 °C. Total RNA still sufficient for RT-qPCR after 12 hours at 37 °C (two donors).
No Genomic DNA Rise
Over 7 days at room temperature, plasma DNA in TFLB showed no genomic DNA rise, matching Streck and PAXgene DNA tubes, while the K2EDTA cfDNA fraction fell to 22 percent by Day 3 (two donors, no statistical testing).
No Proteinase K Step
One 20-minute, 60 °C incubation and $2.30 to $3.25 of enzyme per sample removed from the MagMAX Cell-Free DNA Isolation Kit workflow, compared with Streck Cell-Free DNA BCT (Thermo Fisher MAN0014327).
The TFLB Advantage for Your Laboratory
For Liquid Biopsy Researchers
Collect at distributed sites and process on your schedule. TFLB does not need the 2- to 4-hour processing window that K2EDTA requires.
For Assay Developers
Put TFLB beside your current tube in your own assay. Request evaluation tubes for paired draws below.
For CLIA Lab Directors
On the MagMAX Cell-Free DNA Isolation Kit, TFLB plasma skips the Proteinase K digestion specified for Streck Cell-Free DNA BCT plasma: $2.30 to $3.25 of enzyme per sample and one 20-minute, 60 °C incubation per run.
Experience the New Standard in Pre-Analytical Stability.
Request a TFLB Evaluation KitRequest the Technical NoteWe develop patented reagents to improve molecular tests of solid tissues, blood, and pathogens while supporting industry standard pathology protocols and high throughput lab systems.
ABOUT TRUCKEE APPLIED GENOMICS
TAG develops reagents to improve molecular diagnostics sample quality to accelerate the growth and promise of precision medicine.
TAG's proprietary sample storage and transport reagents are designed to optimize molecular assays with a wide range of applications such as next-generation sequencing, RT-PCR, immunoassays, liquid biopsies, and single cell and spatial genomics.
contact us at +1.775.237.8799, or email info@tagreagents.com.
Let’s discuss your
molecular testing
reagent needs.
Truckee Applied Genomics, Inc.
email: info@tagreagents.com
call or text: +1 775.237.8799
Located in the beautiful Tahoe / Reno region. Close to Bay Area tech resources, yet offering an outstanding quality of life.
275 Hill Street - Suite 290, Reno, NV 89501
